Two major cities in the U.S. are New York City and Los Angeles

New York City and Los Angeles are two of the most prominent and populous cities in the United States, serving as major hubs for finance, culture, and industry. New York City is the most populous city in the U.S. and a global financial center, while Los Angeles is the second-largest city by population and a center for entertainment and international trade.

New York 

City City Population: 

Over 8.4 million.

Los Angeles 

City

Population: Approximately 3.88 million.